⁠⁠Chronic Lymphocytic Leukemia

⁠Chronic Lymphocytic Leukemia (CLL)

Overview

Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the bone marrow and blood. It's a slow-growing cancer that usually develops in middle age or later.

A type of cancer of the blood and bone marrow. B-cell chronic lymphocytic leukemia (CLL) develops from a type of white blood cell called B cells. It progresses slowly, usually affecting older adults. CLL may not cause any symptoms for years. When symptoms do occur, they may include swollen lymph nodes, fatigue and easy bruising. Treatment isn't always initially necessary, but may include chemotherapy and targeted therapy. Stem-cell transplant is used in rare cases for aggressive types.

Symptoms swollen lymph nodes and feeling tired.

Risk factors Age, Family history of CLL, and Exposure to benzene or herbicides like Agent Orange.

Treatment

• CLL can't usually be cured, but it can be managed with treatment
• Treatment may not be needed right away if CLL doesn't cause symptoms
• Doctors monitor CLL and reserve treatment for when it progresses

Diagnosis

• Blood tests can help diagnose CLL
• Immunophenotypic analysis of peripheral blood can also help diagnose CLL

CLL is also known as small lymphocytic lymphoma (SLL). In CLL, B cell lymphocytes can build up in the blood, lymph nodes, spleen, and bone marrow CLL is one of the most common types of leukemia in adults. CLL is rare in children